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Reishi Mushroom

Reishi Mushroom

  1. 1. Composition
  2. 2. Healing Properties
    1. 2.1. Antimicrobial
      1. 2.1.1. Antiviral
      2. 2.1.2. Antiprotozoal
    2. 2.2. Antiallergy
    3. 2.3. Anticancer
      1. 2.3.1. Antitumor
      2. 2.3.2. Antiproliferative
    4. 2.4. Antiaging
    5. 2.5. Cardiovascular Health
      1. 2.5.1. Circulation
        1. Anticoagulant
    6. 2.6. Immune System
      1. 2.6.1. Immunomodulator
  3. 3. Disease / Symptom Treatment
    1. 3.1. Arthritis
    2. 3.2. Bronchitis
    3. 3.3. Cancer
      1. 3.3.1. Breast Cancer
      2. 3.3.2. Skin Canccer
      3. 3.3.3. Bladder Cancer
      4. 3.3.4. Liver Cancer (Hepatoma)
      5. 3.3.5. Leukemia
    4. 3.4. Hepatitis
    5. 3.5. Diabetes

Reishi Mushroom (Lingzhi, Ganoderma lingzhi, Ganoderma lucidum)


Polysaccharides extracted from G. Lucidum have been regarded as an important class of anticoagulants, immunomodulating and antitumour with antioxidant activities, antiproliferative activities, antiviral and antiprotozoal activities.[1]

Bioactive Compounds:

    • (1→3)-β-D-glucans
      • Inhibition of growth of sarcoma tumours[1:1]
    • PS-G,protein-bound polysaccharides (95% polysaccharides and 5% peptides)
      • Activation of the immune response, stimulation of the IL1β, IL-6, TNF-α, and IFN-γ production by macrophages and T lymphocytes, Inhibition of neutrophil apoptosis, Induction of neutrophil phagocytosis, Induction of GST.[1:2]
    • G009, amino polysaccharides
    • Glycoproteins (with fucose)
      • Stimulation of IL-1, IL-2 and IFN-γ expression in spleen cells.[1:4]
    • GLIS, proteoglycans
      • Activation of b-lymphocytes[1:5]
    • Ganoderic acid (U, V, W, X, Y)
      • Cytotoxic for hepatoma cells.[1:6]
    • Ganoderic acid (A, C)
      • Inhibition of farnesyl protein transferase.[1:7]
    • Lucidimol (A, B), Ganodermanondiol, Ganoderiol F, Ganodermanontriol
      • Cytotoxic for sarcoma and lung carcinoma cells.[1:8]
    • Ganoderic acid F
      • Inhibition of angiogenesis.[1:9]
    • Phenols
      • Antioxidant
    • Lipids
      • Growth inhibition of hepatoma, sarcoma S-180 and reticulocyte sarcoma L-II in vivo.[1:10]

Healing Properties







Polysaccharides from Ganoderma lucidum have potential antitumour activities.[1:11]



Cardiovascular Health



Immune System


Polysaccharides from Ganoderma lucidum have potential immunomodulation activities.[1:12]

Disease / Symptom Treatment




Breast Cancer

Polysaccharides from Ganoderma lucidum induce apoptosis of human breast cancer cells.[1:13]

Skin Canccer

Reishi mushroom has become recognized as an alternative adjuvant in the treatment of carcinoma.[1:14]

Bladder Cancer

Ling-Zhi polysaccharides potentiate cytotoxic effects of anticancer drugs against drug-resistant urothelial carcinoma cells.[1:15]

Liver Cancer (Hepatoma)

Ganoderma lucidum has onhibitory effects on tumorigenesis and metastasis of human hepatoma cells.[1:16]


Reishi mushroom has become recognized as an alternative adjuvant in the treatment of leukaemia.[1:17]


Reishi mushroom has become recognized as an alternative adjuvant in the treatment of hepatitis.[1:18]


Reishi mushroom has become recognized as an alternative adjuvant in the treatment of diabetes.[1:19]

  1. Title: Ganoderma lucidum Polysaccharides Extraction, yields and its Biological Applications
    Publication: Electronic Journal of Biology
    Date: August 2020
    Study Type: Fungal Study, Meta Analysis
    Author(s): Yugandhar Parepalli, Murthy Chavali, Sudhakar Reddy Pamanji, Meenakshi Singh
    Institutions: Vignan’s Foundation for Science, Technology & Research, Andhra Pradesh, INDIA; Shree Velagapudi Rama Krishna Memorial College (SVRMC), Nagaram Guntur District, Andhra Pradesh, INDIA; Narayana Medical College & Hospital, Chinnaravuru, Tenali, Guntur District, Andhra Pradesh, INDIA; Vikrama Simhapuri University Post-Graduate Centre, Kavali, Andhra Pradesh, INDIA; The Maharaja Sayajirao University of Baroda, Vadodara 39000, Gujarat, INDIA
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