Article Outline
  1. 1. Composition
  2. 2. Healing Properties
    1. 2.1. Antimicrobial
      1. 2.1.1. Antifungal
  3. 3. Disease / Symptom Treatment
  4. 4. Adverse Affects
  5. 5. Synergistic Effects


Guayusa (Ilex guayusa Loes.) is grown in the Amazonian territories of southern Colombia, northern Peru, and Ecuador.


The main compounds present in the guayusa extracts were caffeine, squalene and -amyrin.[1]

Healing Properties



Some extracts obtained from guayusa leaves showed antifungal activity.[1:1]

Disease / Symptom Treatment

Adverse Affects

Synergistic Effects

  1. Title: A critical review of the composition and history of safe use of guayusa: a stimulant and antioxidant novel food
    Publication: Critical Reviews in Food Science and Nutrition
    Date: August 2019
    Study Type: Review
    Author(s): Graham Wise & Adam Negrin
    Institution(s): University of Wisconsin-Milwaukee, USA; Lehman College, Bronx, New York, USA
    IPFS:, cloudflare ↩︎ ↩︎